drug development support

Medical Solutions™ offers state-of-the-art genomics facilities, underpinned by tissue analysis laboratories to provide prognostic, diagnostic and therapeutic testing supporting drug discovery and patient enrichment for clinical trials. Our fast throughput histology, staining and image analysis platform can provide pharmaceutical and biotechnology companies with rapid, high quality results to facilitate biomarker validation for FDA submission studies. Using the most advanced scientific knowledge and molecular biology techniques, support is offered for patient stratification for clinical trials as well as development of new surrogate biomarkers for cancer and other therapeutic areas. Our services include tissue pathology to gene expression profiling and mutation analysis as well as clinical trial support.

tissue pathology

Basic histology services include processing of tissue to block, sectioning; H & E and pathology review are also offered. Specialist staining including quantitative IHC and FISH can be supplied together with manual and automated image analysis.

pre-clinical testing

We can provide cross-reactivity testing for small molecules and antibodies against FDA and FDA/European recommended lists of tissues.

clinical trial support

Patient enrichment using mutation analysis is offered together with logistics support and supply of manuals and site kits for patient samples. Screening of tissue and body fluids against a variety of markers can be provided together with genome extraction and biobanking. A dedicated study team including principal investigator is provided together with data management and bioinformatics facilities.

patient stratification tests

Gene mutation analysis for the following biomarkers is available to support clinical trials. For further information, please contact our business development team.

• KRAS
• EGFR
• BRAF
• PI3K
• HER2
• P53

how we support the drug development pipeline